DOI: http://dx.doi.org/10.18203/2320-1770.ijrcog20200369

Association between uterine leiomyoma with body mass index and parity in the women of coastal Karnataka, India

Amruta C., Annappa Shetty, Naresh Pawaskar, Shreya Desai

Abstract


Background: Fibroid is the commonest benign tumor of the uterus and also commonest benign solid tumor in females. Fibroids are found to be 2-3 times more prevalent in obese women, specially the one’s with central obesity and in those with BMI > or = 35. Epidemiologic data also shows pregnancy is associated with reduced risk of fibroids. So, the present study will be a cross-sectional study which will be undertaken to know the association of uterine leiomyoma with BMI and parity in the women of coastal Karnataka.

Methods: An analytical cross-sectional study was performed among the 100 patients attending OPD at the department of obstetrics and gynecology, Karwar institute of medical sciences from June 2018 to August 2018. Women suspected to have fibroid based on their symptoms were made to undergo ultrasonography. Comparison was made between the parity, body mass index of the patient and the size of the uterine fibroid visualized.

Results: Out of 100 women studied 63 were nulliparous and 37 women were multiparous. Incidence of fibroid is inversely proportional to parity. When BMI < 18 only 6 women had fibroid, when BMI > 25, 57 women had fibroids and between 18-25 group 37 women were diagnosed with fibroid.

Conclusions: The fibroid showed directly proportional association with BMI. Greater the BMI, more was the risk of fibroids. The fibroid showed inversely proportional association with parity. Greater the parity of the women lesser was her chances of being at risk of having fibroid.


Keywords


Body mass index, Fibroids, Leiomyoma, Parity

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References


Ilma N, Tjahyadi D, Judistiani TD. Relationship of age, parity and body mass index as risk factors to the incidence of uterine myoma in Dr. Hasan Sadikin General Hospital. Althea Med J. 2015;2(3):409.

Stewart EA, Cookson CL, Gandolfo RA, Rath RS. Epidemiology of uterine fibroids: a systematic review. BJOG. An Int J Obstet Gynaecol. 2017;13:1504.

Standard treatment guidelines obstetrics and gynaecology. Ministry of health and family welfare. Government of India. 2016;1(1):5.

Trivedi P, Abreo M. Predisposing factors for fibroids and outcome of laproscopic myomectomy in infertility. J Gynecol Endosc Surg. 2009;1(1):47-56.

Sommer EM, Balkwill A, Reeves G, Green J, Beral D. Effects of obesity and hormone therapy on surgically-confirmed fibroids in postmenopausal women. Eur J Epidemiol. 2015;30(6):493-9.

Stenholm S, Vahtera JH. Body mass index as a predictor of healthy and disease-free life expectancy between ages 50 and 75: a multicohort study. Int J Obesity. 2017;41:769-75.

He Y, Dong ZQ, Qin S, Li G, Wang P. Association between uterine fibroids and lifestyles including diet, physical acivity and stress: a case control study. Asia Pacific J Clin Nutr. 2013;22(1):109-17.

Baird DD, Dunson DB. Why is parity protective for uterine fibroids? PMC. 2013;14:247-8.

Shrestha R, Khanal R, Gottesman A. Fibroid degeneration in a postmenopausal woman presenting as an acute abdomen. J Comm Hospital Intern Med Perspect. 2015;5(1):10.

Sue W, Sarah SB. Radiological appearances of uterine fibroids. The Indian J Radiol Imag. 2009;19(3):222.

den Bosch TV, Dueholm M, Leone FPG. Terms, definitions and measurements to describe sonographic features of myometrium and uterine masses: a consensus opinion from the morphological uterus sonographic assessment (MUSA) group. Ultrasound Obstet Gynecol. 2015;46:284-29.

Babah OA, Oluwole AA, Afolabi BB. Effects of obesity on the development of uterine leiomyoma: a retrospective study of 169 women who had myomectomy in southern. Nigeria J Dent Med Sci. 2014;13:74-8.

Parazzini F. Risk factors for clinically diagnosed uterine fibroids in women around menopause. Maturitas. 2006;55(2):174-9.

Wise LA, Laughlin-Tommaso SK. Epidemiology of uterine fibroids–from menarche to menopause. Clin Obstet Gynecol. 2016;59(1):2-24.

Sato F, Nishi M, Kudo R, Miyake H. Body fat distribution and uterine leiomyomas. J Epidemiol. 1998;8(3):176-80.