Gynandroblastoma: a rare case report of ovarian sex cord tumour

Authors

  • S. Tanouti Department of Obstetrics and Gynecology, Mohammed VI University Hospital Center, Oujda, Morroco
  • I. Elamouri Department of Obstetrics and Gynecology, Mohammed VI University Hospital Center, Oujda, Morroco
  • H. Taheri Department of Obstetrics and Gynecology, Mohammed VI University Hospital Center, Oujda, Morroco
  • H. Saadi Department of Obstetrics and Gynecology, Mohammed VI University Hospital Center, Oujda, Morroco
  • A. Mimouni Department of Obstetrics and Gynecology, Mohammed VI University Hospital Center, Oujda, Morroco

DOI:

https://doi.org/10.18203/2320-1770.ijrcog20200381

Keywords:

Chirurgical treatment, Malignant potential, Rare ovarian tumor, Serum tumor marker

Abstract

Gynandroblastoma is an extremely rare ovarian sex cord tumor with malignant potential. An 61-year-old woman, menopausic, consulted for an abdominal pelvic mass. a latero-uterine mass measuring 27.8 cm in diameter showed a predominantly cystic pattern with a partial solid component. A unilateral adnexectomy was performed. A histopathological examination showed gynandroblastoma composed of juvenile granulosa and Sertoli-Leydig cells, chirurgical treatment was completed by total hysterectomy with right adnexectomy, omentectomy with no proof of malignant cells. We opted for a close observation without adjuvanted chemotherapy. two years after surgery, no signs of recurrence have been noted. The present findings can help clinicians make an accurate preoperative imaging diagnosis of gynandroblastoma with a juvenile granulosa cell component and plan an adequate treatment strategy for this rare, potentially malignant neoplasm.

References

Meyer R. The pathology of some special ovarian tumors and their relation to sex characteristics. Am J Obstet Gynecol. 1931;22:697-713.

Morris JML, Scully RE. In: Endocrine pathology of the ovary. St-Louis: CV Mosby; 1958:97.

Novak ER. Gynandroblastome of the ovary. Review of 8 cases from the ovarian tumor registry. Obstet Gynecol. 1967;30:709-15.

Langley FA. In: Fox H, Langley FA, editors. Postgraduate obstetrical and gynaecological pathology. Oxford: Pergamon Press; 1973:225.

Luca V, Halalau FL, Oprescu I, Palos N, Florea O. Gynandroblastoma of the ovary. Morphol Embryol Physiol. 1983;29:117-20.

Scully RE. Tumors of the ovary and madeveloped gonads. In: Atlas of the tumor pathology, 3rd series, Fasc. 23. Washington, D.C.: Armed Forces Institute Pathol; 1998:219.

Martin-Jimenez A, Condom-Munro E, Valls-Porcel M, Giné-Martin L, Del Amo E, Balaguero-Llado L. Gynandroblastome de l’ovaire. Revue de la literature. J Gynecol Obstet Biol Reprod (Paris). 1994;23:391-4.

McCluggage WG, Sloan JM, Murnaghan M, With R. Gynandroblastoma of the ovary with juvenile granulosa cell component and heterologous intestinal type glands. Histopathol. 1996;29(3):253-7.

Broshears JR, Roth LM. Gynandroblastoma with element resembling juvenile granulosa cell tumor. Int J Gynecol Pathol. 1997;16(4):387-91.

Downloads

Published

2020-01-28

Issue

Section

Case Reports