Study of thrombocytopenia in pregnancy: clinical presentation and outcome at tertiary care rural institute


  • Jigyasa Singh Department of Obstetrics and Gynecology, UPUMS, Saifai, Etawah, Uttar Pradesh, India
  • Kalpana Kumari Department of Obstetrics and Gynecology, UPUMS, Saifai, Etawah, Uttar Pradesh, India
  • Vandana Verma Department of Obstetrics and Gynecology, UPUMS, Saifai, Etawah, Uttar Pradesh, India



Gestational thrombocytopenia, Hemolysis elevated liver enzymes and low platelets, Massive hemorrhage, Puerperal sepsis, Renal failure, Thrombocytopenia in pregnancy


Background: Platelet count below 1.5 lakh/cumm is called as thrombocytopenia. After anaemia it is the second most common haematological disorder in pregnancy. It affects nearly 6 to 15%; on an average 10% of all pregnancies. Gestational thrombocytopenia is a clinically benign thrombocytopenic disorder usually occurring in late pregnancy. It resolves spontaneously after delivery.

Methods: It is a hospital based prospective observational study over a period of 1 year. All pregnant women who attended OPD at the department of obstetrics and gynecology, UPUMS, Saifai for antenatal checkup were included for the study and blood sample was withdrawn.

Results: Out of 263 cases enrolled for study, 90 women were found to have thrombocytopenia, and 173 had normal platelet count. Thus, incidence of thrombocytopenia was 34%. Gestational thrombocytopenia accounted for majority of cases of thrombocytopenia in pregnancy (50%) followed by hypertensive disorders (22.4%). It was further followed by ITP (11.11%) and dengue (5.5%).

Conclusions: Gestational thrombocytopenia is the most common cause of thrombocytopenia during pregnancy (50%), but other underlying causes must be considered as well. A thorough history and physical examination will rule out most causes.


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