DOI: http://dx.doi.org/10.18203/2320-1770.ijrcog20201823

Malignant degeneration of cystic teratoma of the ovary: two cases report

Asma Hmila, Hafsa Taheri, Hanane Saadi, Ahmed Mimouni

Abstract


The malignant degeneration of mature ovarian teratomas is a rare phenomenon. Case reported two cases of squamous cell carcinoma developed on mature teratoma of the ovary in patients aged 54 and 41 who were seen for chronic pelvic pain. Their pelvic ultrasound showed cystic double-component images with sizes of 103 and 95 mm respectively suggestive of dermoid cysts, and the anatomopathological study of the pieces of adnexectomy confirmed the diagnosis. Although no clinical, radiological or biological signs are specific, ovarian dermal cyst degeneration is suspected in the presence of a large dermoid cyst in a postmenopausal or peri-menopausal woman. The careful anatomo-pathological study of the cyst in this case makes it possible to pose the diagnosis of certainty. A rare complication of the dermoid cyst, its prognosis is pejorative and depends mainly on its clinical stage at the time of diagnosis and the quality of its surgical treatment which must be as radical as possible.


Keywords


Ovary, Prognosis, Squamous cell carcinoma, Teratome, Treatment

Full Text:

PDF

References


Wei F, Jiang Z, Yan C. Analysis of 20 mature ovarian cystic teratoma cases in postmenopausal women. Chin Med J Eng. 2001;114:137-8.

Rim SY, Kim SM, Choi HS. Malignant transformation of ovarian mature cysticteratoma. Int J Gynecol Cancer. 2006;16:140-4.

Stamp GW, McConnell EM. Malignancy arising in cystic ovarian teratomas. A report of 24 cases. Br J Obstet Gynaecol. 1983;90:671-5.

Guedira I, Znagui R, Boukhanni L, Haqqi L. Tératome cancérisé de l’ovaire. Gynécol Obstét Fertil. 2011:39.

Ziyadi M, Hakim I, Guelzim K, Kouach J, Moussaoui D, Dehayni M. Teratome mature cancerise De L’ovaire: A Propos D’un Cas Et Revue De La Litterature. Global J Med Res. 2015;15(3):1-3.

Rekhi B, Parikh P, Deodhar KK, Menon S, Maheshwari A, Kerkar R. Squamous carcinoma coexistent with teratoma of ovary: A clinicopathological study of 12 cases diagnosed over a 10-year period ata tertiary cancer referral center. J Can Res Ther. 2015;11:211-5.

Patni R. Squamous cell carcinoma arising in mature cystic teratoma of ovary. J Mid-life Health. 2014;5:10.

Kido A, Togashi K, Konishi I, Kataoka ML, Koyama T, Ueda H. Dermoid cysts of the ovary with malignant transformation: MR appearance. AJR Am J Roentgenol. 1999;172:445-9.

Karim A, Youbi ZA, Benchakroun N, Jouhadi H, Benider A, Sahraoui S, et al. Cancerization d’un kyste dermoid de l’ovaire : à propose d’un cas. Researchfr. 2015;2:1289.

Chiang AJ, La V, Peng J, Yu KJ, Teng NN. Squamous cell carcinoma arising from mature cystic teratoma of the ovary. Int J Gynecol Cancer. 2011;21:466-74.