Published: 2020-03-25

Partial hydatidiform mole evolving into metastatic trophoblastic tumor: case report

I. Elamouri, S. Tanouti, H. Taheri, H. Saadi, A. Mimouni


Partial hydatidiform mole can evolve into a metastatic trophoblastic tumor. A 36-year-old, multiparous woman, pregnant with a 22-week embryonic hydatidiform mole, having spontaneously expelled. Histopathological examination showed a non-invasive partial mole. During biological monitoring, a trophoblastic tumor was diagnosed with pulmonary metastasis on CT-scan and myometrial invasion by MRI. Authors opted for a monochemotherapy with a good evolution. The potential risk of malignant transformation of the partial hydatidiform mole requires an adequate therapeutic strategy with strict monitoring.


22 weeks amenorrhea, Chemotherapy, Myometrial invasion, Partial hydatidiform mole, Pulmonary metastasis, Trophoblastic tumor

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