Solitary splenic metastasis in a case of treated cervical cancer: a case report

Shetty Theertha Shankar, Mangesh Panse, Arjun Goel


Cervical cancer is the second most common cancer among women worldwide and metastasis to the spleen is a rare entity, with only few cases being reported.  The present case of a 55-year-old patient diagnosed with a splenic lesion 3 years following completion of chemotherapy combined with radiotherapy for advanced cervical cancer. The patient underwent diagnostic laparoscopy with splenectomy. The histopathological studies confirmed the presence of a metastatic squamous cell carcinoma (in a known case of treated cervical cancer). At one-year follow-up after splenectomy, the patient was free of any recurrent disease. Owing to its rarity and scant data available, detailed workup should be done whenever a solitary lesion in the spleen is detected on follow-up since splenectomy is the apt management which is instrumental in preventing further complications and improves the survival rates.


Carcinoma, Cervix, Metastasis, Solitary

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Bhandari V, Kausar M, Naik A, Batra M. Unusual metastasis from carcinoma cervix. The J Obstet Gynecol India. 2016;66(5):358-62.

Bellefqih S, Mezouri I, Khalil J, Diakità A, Khannoussi BE, Kebdan T. Skin metastasis of cervical cancer: About an unusual case. J Clin Case Rep. 2013;3(284):2

Senthil R, Mohapatra RK, Srinivas S, Sampath MK, Sundaraiya S. Unusual presentation of metastatic carcinoma cervix with clinically silent primary identified by 18F-flouro deoxy glucose positron emission tomography/computed tomography. Indian J Nucl Med. 2016;31:134-7.

Nag P, Bhandari V, Kausar M, Goyal H. Duodenal metastasis from carcinoma cervix: An unusual presentation and review of literature. Clin Cancer Invest J. 2016;5:166-8.

Thakur P, Verma V, Fotedar V, Sharma M. Femur metastasis: a rare metastatic site in carcinoma cervix. J Case Reports. 2018;8(2):95-7.

Bacalbasa N, Balescu I, Marcu M, Oprescu DN, Anca AF. Solitary splenic metastasis after surgically-treated cervical cancer-a case report and literature review. Anticancer Res. 2017;37(5):2615-8.

Dixit J, Mohammed N, Shetty P. Splenic metastasis from cancer of uterine cervix-a rare case. Indian J Surg Oncol. 2016;7(4):479-83.

Kausar M, Ladia DD, Mutneja A, Bhandari V. Unusual skeletal muscle metastasis from carcinoma cervix. J Cancer Metastasis Treat. 2016;2:67-9.

Yetmen Ö, Öksüz DÇ, Demirkıran F, Özgüroğlu M, Calay Z, Atkovar G, et al. Unusual presentation of cervical carcinoma metastasis to the breast: a case report and review of the literature. Meme Sagligi Dergisi/J Breast Health. 2012;8(2):92-6.

Pandey D, Shetty J, Sambhaji C, Saxena PU, Mishra D, Chawla A. Cervical Cancer as a silent killer: A rare case report with review of literature. J Can Res Ther. 2015;11:653.

Pang LC. Solitary recurrent metastasis of squamous cell carcinoma of the uterine cervix in the spleen: case report. South Med J. 2004;97(3):301-4.

Koh YS, Kim JC, Cho CK. Splenectomy for solitary splenic metastasis of ovarian cancer. BMC Cancer. 2004;4:96

Piura B, Rabinovich A, Apel-Sarid L, Shacol-Levy R. Splenic metastasis from endometrial carcinoma: report of a case and review of literature. Arch Gynecol Obstet. 2009;280(6):1001-6.

Gupta TT. Splenic metastases from cervical carcinoma: a case report. International J Gynecol Cancer. 2006;16(2):911-4.

Applebaum M, Schulz B. Isolated splenic metastasis in a patient with squamous cell carcinoma of the cervix. Applied Radiol. 2017:24-5.

Taga S, Sawada M, Nagai A. Splenic metastasis of squamous cell carcinoma of the uterine cervix: a case report and review of the literature. Case Reports Obstet Gynecol. 2014;2014:1-4.