An encounter with alobar holoprosencephaly: a case report
DOI:
https://doi.org/10.18203/2320-1770.ijrcog20202761Keywords:
Alobar, Cyclopia, Holoprosencephaly, Proboscis, Recurrence, Sporadic, TerminationAbstract
Alobar holopresencephaly is a rare embryonic condition where there is anomalous fusion of cerebral hemispheres. The key features include neurological impairment and facial dysmorphism like cyclopia, ocular hypertelorism with divided orbits and a proboscis. Obstetric ultrasound and foetal MRI are the diagnostic modalities. Majority of cases are sporadic in origin while a genetic association is also described. A small recurrence risk is noted in cases with sporadic origin. Early diagnosis and pregnancy termination are advisable for the condition since the survival rate is very low.
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