Vitamin D deficiency and adverse fetal outcome
DOI:
https://doi.org/10.18203/2320-1770.ijrcog20202728Keywords:
Apgar score, Neonatal intensive care unit, Still birth, Vitamin D deficiencyAbstract
Background: Vitamin D deficiency is recognized as the most untreated nutritional deficiency in the world. It is plausible that vitamin D deficiency could make the fetal heart more vulnerable to distress/birth asphyxia. Vitamin D deficiency has been hypothesized to be associated with low birth weight, low Apgar score at birth, higher rates of still births and admission to NICU. The aim of present study was to study prevalence of vitamin D deficiency in pregnancy and evaluate perinatal outcome.
Methods: The study was conducted in the department of obstetrics and gynecology, Kamla Nehru Hospital, Shimla, India over a period of 12 months. Six hundred women were included in the study.
Results: All the mothers who had still births suffered from vitamin D deficiency and the severe vitamin D deficiency was there in 90.91% (30) of these subjects. Severe vitamin D deficiency was seen in 78.95% (75) of the subjects having babies with birth weights <2.5 kg compared to 61.16% (288) subjects of the other group.
Conclusions: Adverse fetal outcome are more common in vitamin D deficient group.
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References
Prasad D, Smita, Singh K, Nisha S. Vitamin D in pregnancy and its correlation with feto maternal outcome. Int J Contemp Med Res. 2018;5(1):1-5.
Singh N, Kumar D, Singh J, Chandanan A. A study of vitamin D, its supplementation and effect on fetomaternal outcome during pregnancy. Indian J Res. 2015;4(9):270-2.
Lindqvist PG, Silva AT, Gustafsson SA. Gidl of Sebastian. Maternal vitamin D deficiency and fetal distress/birth asphyxia: a population based nested case-control study. BMJ Open. 2016;6:e009733.
Royal college of obstetricians and gynecologists. vitamin D in pregnancy. Scientific Impact Paper No 43. London: RCOG; 2014.
Chauhan N, Pahuja N, Kalra V. Correlation of Vitamin D levels with feto-maternal outcome. Int J Reprod Contracept Obstet Gynecol. 2017;7(1):137-41.
Nageshu S, Krishna K, Krishna L, Bhat B, Suma H, Reddy S. A study of prevalence of Vitamin D deficiency among pregnant women and its impact on feto maternal outcome. Int J Reprod Contracept Obstet Gynecol. 2016;4(4):1174-80.
Dave A, Verma AM, Jain N, Dave A. A study of vitamin D levels and associated deficiency in pregnancy and its effect on maternal and fetal outcome. Int J Reprod Contracep Obstet Gynecol. 2017;6(1):84-8.