Prevalence and outcome of gestational diabetes mellitus in women from rural population attending antenatal clinic at a teaching hospital, Tamil Nadu, India


  • Vidhya Muthuramalingam Department of Obstetrics and Gynecology, Karpaga Vinayaga Institute of Medical Sciences and Research Centre, Madhuranthagam, Tamil Nadu, India
  • Amar Nagesh Kumar Department of Biochemistry, Karpaga Vinayaga Institute of Medical Sciences and Research Centre, Madhuranthagam, Tamil Nadu, India



Antenatal women, Gestational diabetes, Macrosomia, Pre-eclampsia, Prevalence


Background: Prevalence of gestational diabetes mellitus shows wide variation across our country. From the recent studies, it is observed that incidence of gestational diabetes mellitus in antenatal women is increasing globally and India is not an exception from this. Gestational diabetes mellitus should be considered as a serious risk factor for both mother and baby as it affects two generations by having chance of developing diabetes and its related complications in future.

Methods: A total of 585 pregnant women with 24 to 28 weeks of gestational age were recruited for the study. The study population was divided into four groups based on the age range; Group I include antenatal women with age <20 years, Group II includes antenatal women of age range 21-24 years, Group III includes antenatal women of age range 25-29 years, and Group IV includes antenatal women of age range ≥30 years.

Results: In the present study GDM was diagnosed in 94 women among 585 antenatal women screened for GDM (16.06%). Majority of the studied population are in the age range of 20-29 years (441/585, 75.38%). The mean age of participants was 27.54±3.58 years (range 18-34 years). The prevalence of GDM was higher in the group of women aged ≥30 years (Group IV) followed by ≤20 years (Group I) (23.21% and 15.62% respectively) compared to the groups II and III (14.78% and 13.74% respectively). This observation was found to be statistically significant (p<0.001). Among 585 patients, delivery outcome was 100% successful, all delivered live babies, among them 64 patients delivered babies with macrosomia (11%).

Conclusions: The study showed GDM prevalence of 16.06% from the neighboring rural villages attending our teaching hospital.


Joshi SR, Parikh RM. India - diabetes capital of the world: now heading towards hypertension. J Assoc Physicians India. 2007;55:323-4.

Gasim T. Gestational diabetes mellitus: maternal and perinatal outcomes in 220 Saudi women. Oman Med J. 2012;27(2):140.

Wendland EM, Torloni MR, Falavigna M, Trujillo J, Dode MA, Campos MA, et al. Gestational diabetes and pregnancy outcomes-a systematic review of the World Health Organization (WHO) and the International Association of Diabetes in Pregnancy study groups (IADPSG) diagnostic criteria. BMC Pregnancy Childbirth. 2012;12(1):23.

Kanguru L, Bezawada N, Hussein J, Bell J. The burden of diabetes mellitus during pregnancy in low-and middle-income countries: a systematic review. Glob Health Action. 2014;7(1):23987.

Carr DB, Utzschneider KM, Hull RL, Tong J, Wallace TM, Kodama K, et al. Gestational diabetes mellitus increases the risk of cardiovascular disease in women with a family history of type 2 diabetes. Diabetes Care. 2006;29(9):2078-83.

Nagy K, Pomucz J, Varga R, Szabo E, Soltesz G. Anthropometric data, fetal and neonatal complications in infants of diabetic mothers. Results of a 10 year retrospective study. Orv Hetil. 2013;154(5):172-7.

Shah BR, Retnakaran R, Booth GL. Increased risk of cardiovascular disease in young women following gestational diabetes mellitus. Diabetes Care. 2008;31(8):1668-9.

Retnakaran R, Shah BR. Mild glucose intolerance in pregnancy and risk of cardiovascular disease: a population-based cohort study. Can Med Assoc J. 2009;181(6-7):371-6.

World Health Organization. Diagnostic criteria and classification of hyperglycaemia first detected in pregnancy. Diabetes Res Clin Pract. 2014;37(1):S14-80.

Siribaddana SH, Deshabandu R, Rajapakse D, Silva K, Fernando DJ. The prevalence of gestational diabetes in a Sri Lankan antenatal clinic. Ceylon Med J. 1998;43:88-91.

Seshiah V, Balaji V, Balaji MS, Sanjeevi CB, Green A. Gestational diabetes mellitus in India. J Assoc Physicians India. 2004;52:707-11.

Ginige PS. Prevalence and pregnancy outcome of gestational diabetes mellitus (GDM) in Homagama DDHS area and validation of selected screening methods to detect GDM. Post Graduate Institute of Medicine, University of Colombo; 2004.

Seshiah V, Balaji V, Balaji MS, Paneerselvam A, Arthi T, Thamizharasi M, et al. Prevalence of gestational diabetes mellitus in South India (Tamil Nadu) - a community-based study. J Assoc Physicians India. 2008;56:329-33.

Mahalakshmi MM, Bhavadharini B, Maheswari Kumar RM, Shah SS, Bridgette A, Choudhury M, et al. Clinical profile, outcomes, and progression to type 2 diabetes among Indian women with gestational diabetes mellitus seen at a diabetes center in south India. Indian J Endocrinol Metab. 2014;18:400-6.

Padmanabhan S, Wagstaff A, Tung V, Chan YF, Bartlett A, Lau SM. Increase in body mass index during pregnancy and risk of gestational diabetes. Diabetes Res Clin Pract. 2014;106:79-82.

Flores-Padilla L, Solorio-Páez IC, Melo-Rey ML, Trejo-Franco J. Pregnancy and obesity: risk of developing gestational diabetes in the northern border area of Mexico. Gac Med Mex. 2014;150:73-8.

Duman NM. Frequency of gestational diabetes mellitus and the associated risk factors. Pak J Med Sci. 2015;31:194-7.

Khan R, Ali K, Khan Z. Socio-demographic risk factors of gestational diabetes mellitus. Pak J Med Sci. 2013;29:843-6.

Martin KE, Grivell RM, Yelland LN, Dodd JM. The influence of maternal BMI and gestational diabetes on pregnancy outcome. Diabetes Res Clin Pract. 2015;108:508-13.

Beucher G, Viaris de Lesegno B, Dreyfus M. Maternal outcome of gestational diabetes mellitus. Diabetes Metab. 2010;36(6 Pt 2):522-37.






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