Primary malignant melanoma of vagina: a case report


  • Smruti Gedam Department of Obstetrics and Gynecology, Government Medical College and Hospital, Nagpur, Maharashtra, India
  • Tarachand Sharma Department of Obstetrics and Gynecology, Grant Medical College and JJ Group of Hospitals, Mumbai, Maharashtra, India



Amelanotic melanoma, Primary malignant melanoma, Vaginal melanoma


Primary malignant melanoma of the vagina is a rare and aggressive disease with worse prognosis as compared with non-genital melanomas or other vaginal malignant neoplasms. Presented here is a case of 42 years female with 3 months history of amenorrhea and vaginal discharge. On vaginal examination, a firm growth of size approximately 7-8 cm was found attached to the left postero-lateral wall of vagina and extending up to the introitus. On biopsy and histopathological examination, it was diagnosed as a case of high-grade malignant melanoma of amelanotic type. Radiotherapy was started as a part of treatment after consultation with an oncologist, considering non-resectable nature of the mass. The patient received first 5 cycles of radiotherapy but succumbed to the disease during treatment.


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