DOI: http://dx.doi.org/10.18203/2320-1770.ijrcog20203065

Experience with women having uterine cancer in Eastern India: a hospital based study

Priyanka Singh, Chandrima Ray, Ranajit Mandal

Abstract


Background: The changing lifestyle has led to a rise in obesity, diabetes and hypertension in India which the most important risk factors for developing uterine cancer. The treatment of uterine cancer is evolving and requires proper evaluation and often adjuvant treatment for better survival. The disease being associated with symptoms of abnormal uterine bleeding often ends up being inadequately managed by non-oncologists practicing in a generalist setting in India. The current study was aimed to audit and observe any difference in outcome of patients primarily treated in the oncology set-up of the Chittaranjan National Cancer Institute, which is a regional cancer center in India versus those receiving primary treatment in a non-oncological set-up.

Methods: Retrospective data was collected from hospital records after setting inclusion and exclusion criteria for the study.

Results: There is poor correlation between the endometrial biopsy and histopathology findings of patients operated in non-oncological setting as compared to that in the institute. The overall survival of patients operated in the institute was superior to those treated outside.

Conclusions: Patients having risk factors and symptoms akin to that of uterine carcinoma must be treated in an oncological set-up ideally.


Keywords


Endometrial carcinoma, Gynecologic oncology, Hysterectomy

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References


Setiawan VW, Yang HP, Pike MC, McCann SE, Yu H, Xiang YB, et al. Type I and II endometrial cancers: have they different risk factors? J Clin Oncol. 2013;31(20):2607-18.

Bray F, Ferlay J, Soerjomataram I, Siegel RL, Torre LA, Jemal A. Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin. 2018;68(6):394-424.

Atlas of cancer registry in India; national cancer registry programme, chapter 3-5. Available at: http://www.ncdirindia.org/ncrp/ca/chapter3_5.aspx. Accessed on 6th May 2020.

Ahirwar R, Mondal PR. Prevalence of obesity in India: a systematic review. Diabetes Metab Syndr. 2019;13(1):318-21.

Hacker NF, Friedlander ML. Chapter 9, Uterine cancer. In: Berek and Hacker’s Gynecologic Oncology. 6th Ed Wolters Kluwer; 2015:390-442.

Interrater reliability: the kappa statistic Mary L. McHugh Biochem Med (Zagreb) 2012;22(3):276-82.

RCOG Green-Top guideline No. 67. Available at: https://www.rcog.org.uk. Accessed on 1st June 2020.

NCCN Guideline on Uterine Neoplasm version 1. 2020. Available at: www.nccn.org. Accessed on 1st 2020.

Thomas V, Thomas A, Sebastian A, Chandy R, Peedicayil A. Inadequately staged endometrial cancer: a clinical dilemma. Indian J Surg Oncol. 2018;9(2):166-70.

Pandey A, Ploubidis GB, Clarkec L, Dandonaa L. Trends in catastrophic health expenditure in India: 1993 to 2014. Bulletin WHO. 2018;96:18-28.

Engelen MJ, Kos HE, Willemse PH, Aalders JG, de Vries EG, Schaapveld M, et al. Surgery by consultant gynecologic oncologists improves survival in patients with ovarian carcinoma. Cancer. 2006;106(3):589-98.