The study of antibiotic-sensitivity and resistance pattern of bacteria causing catheter associated urinary tract infection

Authors

  • Abha Singh Department of Obstetrics and Gynecology, Pt. J. N. M. Medical College, Raipur, Chhattisgarh, India
  • Avinashi Kujur Department of Obstetrics and Gynecology, Pt. J. N. M. Medical College, Raipur, Chhattisgarh, India
  • Muthulakshmi M. Department of Obstetrics and Gynecology, Pt. J. N. M. Medical College, Raipur, Chhattisgarh, India
  • Abha Daharwal Department of Obstetrics and Gynecology, Pt. J. N. M. Medical College, Raipur, Chhattisgarh, India

DOI:

https://doi.org/10.18203/2320-1770.ijrcog20203295

Keywords:

Antibiotic resistance, Antibiotic sensitivity, Catheter associated urinary tract infections

Abstract

Background: present study is done to study the antibiotic-sensitivity and resistance pattern of bacteria causing catheter associated urinary tract infection. Objectives of this study were to study the bacterial etiology of CAUTI, to study the prevalence of various bacteria causing catheter associated urinary tract infection, the antibiogram (sensitivity and resistance) pattern of isolated bacteria and the percentage of asymptomatic bacteriuria in the study population.

Methods: In this prospective observational study, under aseptic precautions, urine sample was taken after 48 hours of catheterization and sent for culture and sensitivity pattern is studied.

Results: In this study 500 urine samples were cultured and its antibiotic sensitivity pattern was observed. Out of the 53 culture positive samples most the subjects had asymptomatic bacteriuria. The study gave the incidence of catheter associated urinary tract infection (CAUTI) to be 10.6% and about 9% were polymicrobial. In this study about 7 causative bacteria were isolated. Escherichia coli were the most common organism that was isolated. On studying the antibiotic susceptibility pattern of each isolate, it has been observed that all of them are multidrug resistant and the sensitivity pattern is migrating towards higher antibiotics.

Conclusions: Empirical use of antibiotics must be avoided and antibiotics must be used only after sensitivity testing. This will help in selection of the appropriate antibiotic for therapeutic use and prevent indiscriminate and irrational use of antibiotics. This will also improve the cost efficiency and decrease the duration of hospital stay.

References

Centre for diseases control, device associated module, 2019. Available at: https://www.cdc.gov/nhsn/pdfs/pscmanual/pcsmanual_current.pdf. Accessed on 22nd May 2020.

Leelakrishna P, Karthik Rao B. A study of risk factors for catheter associated urinary tract infection. Int J Adv Med. 2018;5(2):334-9.

Verma S, Naik SA, Deepak TS. Etiology and risk factors of catheter associated urinary tract infections in ICU patients. Int J Med Microbiol Trop Dis. 2017;3(2):65-70.

Sandhu R, Sayal P, Jakkhar R, Sharma G. Catheterization-associated urinary tract infections: Epidemiology and incidence from tertiary care hospital in Haryana. J Health Res Rev. 2018;5:135-41.

Tenke P, Mezei T, Bőde I, Köves B. Catheter-associated urinary tract infections. Euro Urol Suppl. 2017;16(4):138-14.

Mishra D, Bhaskara Rao K, Catheter associated urinary tract infection in an acute care setting of a tertiary care centre in South India. Int J Res Med Sci. 2019;7(6):2182-6.

Mangukiya JD, Patel KD, Vegad MM. Study of incidence and risk factors of urinary tract Infections in catheterized Patients admitted at tertiary care hospital. Int. J of Res Med Sci. 2015;3(12):3808-11.

Gupta T, Prem MP, Ved P, Agarwal P, Premi HK, Kumar A. Spectrum of catheter associated urinary tract infections in the obstetric patients in a tertiary care hospital. Int J Contemp Med Res. 2016;3(11):3349-52.

Bhani D, Bachhiwal R, Sharma R, Maheshwari RK. Microbial profile and antimicrobial susceptibility pattern of uropathogens isolated from catheter associated urinary tract infection (CAUTI). Int J Curr Microbiol Appl Sci. 2017;6:2446-53.

Downloads

Published

2020-07-23

Issue

Section

Original Research Articles