Obesity in pregnancy: maternal and perinatal outcome

Aishwarya V. Gupta, Ami Mehta, Bhargav Patel, Karan Mehta


Background: The objective of this study was to find out the spectrum of complications during pregnancy due to maternal obesity with incidence and to assess the neonatal outcome.

Methods: Retrospective study of antenatal patients was done in Sardar Vallabhbhai Patel Institute of Medical Sciences and Research (SVPIMSR), Ahmedabad from June 2019 to December 2019. Antenatal patients were categorized into 3 classes based on body mass index (BMI): class I=30-34.9 kg/m2, class II=35-39.9 kg/m2, and class III ≥40 kg/m2. The maternal and perinatal outcome of the patients was evaluated in relation to BMI.

Results: A total of 61 women were included in the study, with 44 belonging to class I, 15 women to class II and 2 women to class III. In class I, 27% women had pre-eclampsia and its incidence increased with class II (69.2%) and class III (100%). The incidence of gestational diabetes mellitus (GDM) increases with increase in BMI (class I=5.4%, class II=7.6% and class III=50%). Incidence of fetal growth restriction (FGR) (7.6% and 2.7%) and post term pregnancy (38% and 16.2%) more in class II compared to class I respectively. Lower segment caesarean section (LSCS) rates are seen to be highest in class III (100%) as compared to class II (53%) and class I (50%). Class III (50%) women were more likely to have macrosomic babies than class II (40%) and class I (34.1%).

Conclusions: Interventions directed towards weight loss and prevention of excessive weight gain must begin in the preconceptional period. Obese mothers must be counselled regarding risk and complications of obesity and importance of weight loss.


Maternal outcome, Obesity, Perinatal outcome

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Flier JS, Maratos-Flier E. Biology of obesity. In: Fauci, Braunwald, Kasper, Hauser, Longo, Jameson, Loscalzo. Harrison’s Principles of Internal Medicine. 17th edition. New York: McGraw-Hill. 2008:463.

Cunningham FG, Lenovo KJ, Bloom SL, Hauth JC, Gilstrap L, Wenstrom KD. Obesity. Williams Obstetrics. 24th edition. New York: McGraw-Hill Companies. 2005;946.

Dasgupta A, Harichandrakumar KT, Syed Habeebullah S. Pregnancy outcome among obese Indians - a prospective cohort study in a tertiary care centre in South India. Int J Sci Stud. 2014;2(2):13-8.

O’Brien TE, Ray JG, Chan WS. Maternal body mass index and the risk of preeclampsia: a systematic overview. Epidemiology. 2003;14(3):368-74.

Linne’ Y, Barkeling B, Rossner S. Natural course of gestational diabetes mellitus: long term follow-up of women in the SPAWN study. BJOG. 2003;109(11):1227-31.

Cresswell P, Rasmussen S, Kesmodel U. Effect of pregnancy maternal overweight and obesity on pregnancy outcome. Obstet Gynecol. 2011;118:305-12.

Sebire NJ, Jolly M, Harris JP, Wadsworth J, Joffe M, Beard RW, et al. Maternal obesity and pregnancy outcome: a study of 287,213 pregnancies. Int J Obes Relat Metab Disord. 2001;25(8):1175-82.

Alanis MC, Villers MS, Law TL, Steadman EM, Robinson CJ. Complications of cesarean delivery in the massively obese parturient. Am J Obstetr Gynecol. 2010;203(3):271-7.

Hoegsberg B, Gruppuso PA, Coustan DR. Hyperinsulinemia in macrosomic infants of non-diabetic mothers. Diabetes Care. 1993;16:32-6.

Portman OW, Behrman RE, Soltys P. Transfer of free fatty acids across the primate placenta. Am J Physiol. 1969;216:143-7.

Abenhaim HA, kinch RA Morin L, Benjamin A, Usher R. Effect of pregnancy body mass index categories on obstetrical and neonatal outcomes. Gynec Obst. 2003;21(1):24-8. Pedersen J, Bojsen-Moller B, Poulsen H. Blood sugar in newborn infants of diabetic mothers. Acta Endocrinol. 1954;15:33-52.