DOI: http://dx.doi.org/10.18203/2320-1770.ijrcog20160869

Prevalence and burden of adenomyosis in hysterectomy specimens for benign abnormal uterine bleeding in a tertiary care institute in Pondicherry, India

Vijaya Koothan, Anitha Vijay, Gayatri Maran, Sreelakshmy .

Abstract


Background: Abnormal uterine bleeding (AUB) is one of the most common presenting complaints encountered by women in reproductive age group. An estimated 60% of visits to a physician’s office are from women seeking treatment for menstrual problems. The aim was to assess the burden and prevalence of adenomyosis among hysterectomy specimens for benign causes of AUB in tertiary care institute in Pondicherry.

Methods: In this retrospective study, records were retrieved of the patients and pathological specimens of consecutive 184 hysterectomies for benign abnormal uterine bleeding done between May 2007 and May 2008. Patient characteristics were retrieved, and the frequency of adenomyosis in this group was determined.

Results: A total of 184 hysterectomies were indicated for benign causes of abnormal uterine bleeding - 50 (23.8%) for fibroid, 119 (55.66%,) for adenomyosis, 15 (7.14%) for dysfunctional uterine bleeding, endometrial hyperplasia and others, other than for malignant causes. Age range 33-55 years, mean age was 43.62 years among adenomyosis patients

Conclusions: Adenomyosis was diagnosed in 119 (55.66 %) of the benign AUB specimens. Adenomyosis is a frequent cause for failed conservative management culminating in hysterectomy, posing risk to health related quality of life of women with a bearing on emotional, physical, psychosocial, economic issues and family life.

Keywords


Prevalence of adenomyosis, Benign abnormal uterine bleeding, Hysterectomy

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References


Kjerulff KH, Erickson BA, Langenberg PW. Chronic gynecological conditions reported by US wom- en: findings from the national health interview survey, 1984 to 1992. Am J Public Health. 1996;86:19.

Market Opinion and Research International (MORI). Women’s health in 1990. [Research study con- ducted on behalf of Parke-Davis Laboratories]. London: MORI; 1990.

Barnard K, Frayne SM, Skinner KM, Sullivan LM. Health status among women with menstrual symp- toms. J Womens Health (Larchmt). 2003;12:911-9.

Cote I, Jacobs P, Cumming D. Work loss associated with increased menstrual loss in the United States. Obstet Gynecol. 2002;100:683-7.

Millar W. Hysterectomy, 1981/82 to 1996/97. Health Rep. 2001;12:9-22.

Frick KD, Clark MA, Steinwachs DM, Langenberg P, Stovall D, Munro MG, et al. Financial and quali- ty-of-life burden of dysfunctional uterine bleeding among women agreeing to obtain surgical treatment. Womens Health Issues. 2009;19:70-8.

Schickedanz A, Kalro B, et al. Bleeding problems in mid life. Glob. libr. women's med. 2008; DOI 10.3843/GLOWM.10297.

Singh S, Best C, Dunn S, Leyland N, Wolfman WL, Clinical Practice – Gynaecology Committee, et al Abnormal Uterine Bleeding in Pre-Menopausal Women. J Obstet Gynaecol Can. 2013;35(5):473-9

Liu Z, Doan QV, Blumenthal P, Dubois RW. A Systematic Review Evaluating Health-Related Quality of Life,Work Impairment, and Health-Care Costs and Utilizationin Abnormal Uterine Bleeding. Value Health. 2007;10(3):183-94.

Saheta A. Abnormal uterine bleeding. Journal of Dental and Medical Sciences. 2014;13(11):63-7.

Ghazala R, Pandey H. Histopathological correlation of adenomyosis and leiomyoma in hysterectomy specimens as the cause of abnormal uterine bleeding in women in different age groups in the Kumaon region: A retroprospective study. J Midlife Health. 2013;4(1):27-30.

Vercellini P, Viganò P, Somigliana E, Daguati R, Abbiati A, Fedele L. Adenomyosis: epidemiological factors. Best Pract Res Clin Obstet Gynaecol. 2006;20(4):465-77.

Naftalin J. How common is adenomyosis? A prospective study of prevalence using transvaginal ultra- sound in a gynaecology clinic. Hum Reprod. 2012;27(12):3432-9.

Taran FA, Stewart EA, Brucker S1. Adenomyosis: Epidemiology, risk factors, clinical phenotype and surgical and interventional alternatives to hysterectomy. Gebuurtshife Frauenheild, 2013;73(9);924-31.

Mobarakeh MD, Maghsudi A, Rashidi I. Adenomyosis among samples from hysterectomy due to abnormal uterine bleeding in Ahwaz, southern Iran. Adv Biomed Res. 2012;1:49. doi: 10.4103/2277-9175.100156.

Khreisat B. Adenomyosis: frequency of hysterectomy in histopathological specimens at two Jordanian military hospitals. JRMS. 2011;18(2):76-9

Sordia-Hernandez LH, Herrerob J, Martineza AM, Grisb JM, Rodrigueza DS, Gutierreza OV, et al. Adenomyosis: Pathologies associated in a set of patients un- derwent hysterectomy. Asian Pacific Journal of Reproduction. 2012;1(4):283-6.

Chaturvedi V. Pattern and frequency of uterine pathologies among hysterectomy specimens in rural part of northern India: a retrospective secondary data analysis. Ind J Comm Health. 2014;26(1):103-6.

Mehla S, Singh M, Chutani N. Clinicopathological correlation of adenomyosis and leiomyoma in hysterectomy specimens as the cause of abnormal uterine bleeding: a retroprospective study sch. J App Med Sci. 2014;2(6G):3320-3.

Kim J, Strawn EW. Adenomyosis: A frequent cause of abnormal uterine bleeding. Obstet Gynecol. 2000;95:S23.

Gupta R, Dewan D. Clinicopathological Study on Adenomyosis Uteri Paripex- Indian Journal Of Research. 2015;4(3):6-7.

Pervez SN, Javed K. Adenomyosis among samples from hysterectomy due to abnormal uterine bleeding. J Ayub Med Coll Abbottabad. 2013;25(1-2):68-70.

Pandey D, Sehgal K, Saxena A, Hebbar S, Nambiar J, Bhat RG. An audit of indications, complications, and justification of hysterectomies at a teaching hospital in India. International Journal of Reproductive Medicine. 2014;2014:Article ID 279273.

Ramesh BH, Shashikala P, Chandrasekhar D. A Study of Prevalence and Risk Factors of Adenomyosis at Hysterectomy Indian Jou- nalof Public Health Research & Development. 2013;4(2):203-5.

Karthikeyan TM, Veenaa NN, Kumar CRA, Eliz Thomas E. Clinico-pathological study of hysterectomy among rural patients in a tertiary care center, Journal of Dental and Medical Sciences. 2015;14(5):25-7.

Mohammed N, Prejisha B. A study of correlation of etiological and histopathological findings in females undergoing hysterectomy for abnormal uterine bleeding - in accordance with palmcoein classi- fication. Paripex - Indian journal of research. 2014;3(11):76-8.

Vitamins and hormones. Vitamins and Hormones. Volume 37. Ed. Harris R, Thimann K.