An unusual case of cervical leiomyosarcoma in an adoloscent girl

Sangeeta Pahwa, Arshdeep Kaur, Preet K. Kaur, Tavleen Kaur


Primary leiomyosarcoma of the uterine cervix is an exceedingly rare tumor. It is malignant mesenchymal tumour of smooth muscle origin. We report a case of 15-year-old adolescent girl who presented with complain of excessive bleeding per vaginum off and on since 3-4 months and was diagnosed as leiomyosarcoma of cervix. Patient was advised further management but father refused as according to them when bleeding has stopped completely then what is the need of further treatment. In this article we want to highlight the points: what is prognosis and survival of such patient whose mass was removed completely and patient is not willing for further treatment inspite of knowing the aggressive nature of tumor and if hysterectomy is the answer what about the reproductive outcome in such young girls and what is the prospect of uterine transplant surgery.  


Cervical leiomyosarcoma, Adoloscent age group, Management, Reproductive outcome, Ovarian preservation, Uterine transplant

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Jayaram VK, Parikshith J, Narayanan GS, et al. Multimodality management of leiomyosarcoma of the cervix. Canc Medic Sci. 2018;12:830.

Bansal S, Lewin SN, Burke WM, Deutsch I, Sun X, Herzog TJ, et al. Sarcoma of the cervix: natural history and outcomes. Gynecol Oncol. 2010;118(2):134-8.

Mehra R, Sidhu S, Pandey A, Garg S. A rare case of leiomyosarcoma of cervix and challenges in its management. Int J Res Med Sci. 2015;3(1):320-4.

Fadare O. Uncommon sarcomas of the uterine cervix: a review [2] of selected entities. Diagnost Pathol. 2006;1:30.

Casanova J, Huang KG, Thepsuwan J, Benavides DR, Chi CL. Localized leiomyosarcoma of the uterine cervix with rapid lung metastases. Gynecol Minimal Invasi Thera. 2015;4(3):95-7.

Whitcombe DD, Valente PT, Acosta OM, Kost ER. Leiomyosarcoma of the uterine cervix associated with pregnancy: A case report and review of literature. Gynecol Oncol Rep. 2016;17:45-8.

Dhull AK, Adarsh C, Kaushal V, Marwah N. The uncovered story of leiomyosarcoma of the cervix: a rare case report and review of literature. Cas Repor. 2013;2013:bcr2013008616.

Sutton G, Blessing JA, Malfetano JH. Ifosfamide and doxorubicin in the treatment of advanced leiomyosarcomas of the uterus: a Gynecologic Oncology Group study. Gynecol Oncol. 1996;62(2):226-9.

Aminimoghaddam S, Arabian S, Haghighi S, Haghighi L. Cervical leiomyosarcoma: a case report. J Obstet Gynecol Canc Res. 2016;1(1):e7523.