Epidemiological and diagnostic aspects of spontaneous miscarriage in the department of gynecology-obstetric of the university hospital of Treichville in Abidjan


  • Ignace N. Yao Department of Gynecology-Obstetric of the University Hospital of Treichville, Abidjan
  • Jean Marc L. Dia Department of Gynecology-Obstetric of the University Hospital of Treichville, Abidjan
  • Michelle M. Menin Department of Gynecology-Obstetric of the University Hospital of Bouake
  • Mouhedeen A. Oyelade Department of Gynecology-Obstetric of the University Hospital of Treichville, Abidjan
  • Corneille T. Saki Department of Gynecology-Obstetric of the University Hospital of Treichville, Abidjan
  • Gerard Okon Department of Gynecology-Obstetric of the University Hospital of Treichville, Abidjan




Chromosomal abnormalities, Pregnancy, Spontaneous miscarriages


Background: Describe the epidemiological and diagnostic of spontaneous aspects of early miscarriage in the department of the Gynecology Obsteric of Treichville University Teaching Hospital of   Treichville in Abidjan.

Methods: A cross-sectional study was performed from January 2016 to March 2017 on patients received for an early miscarriage (gestational age less than 14 weeks of amenorrhea).

Results: We recorded 337 cases of miscarriage and it shows that miscarriage was frequently estimated at 58 percent. Our patients had a average age of 32.9 years, 60.4 percent of them with primary education and 48 percent are housewives. The patients were paucigestes in 46 percent and the majority of them were nulliparous (62 percent). 6 percent with history of high blood pressure; diabetes (3 percent) and 31 percent of patients were HIV positive. Patients had pelvic pain at the admission in (55 percent). A miscarriage appears before 10 weeks of amenorrhea (76.1 percent) of cases. Ultrasound showed ovular debris (47 percent) of patients and (55.4 percent) were chromosomal abnormalities on anatomy-pathological examination.

Conclusions: Spontaneous abortions are common and pathological examination is essential for diagnosis.


Blohm F, Friden B, Milson I. A prospective longitudinal population-based study of clinical miscarriage in an urban Swedish population. BJOG. 2008;115:176-82.

Houmaid H, Bekkay C, Nassereddine S, Talbi H, Amehdare L, Hilali A. Chromosomal abnormalities in 238 couples with recurrent miscarriages in Morocco. Open J Genetics. 2018;8:15-22.

Trinder J, Brocklehurst P, Porter R, Read M, Vyas S, Smith L. Management of miscarriage: expectant, medical or surgical? Results of randomised controlled trial miscarriage treatment (MIST). BMJ. 2006;332:1235-40.

Cissé CT, Faye KG, Moreau JC. First trimester abortions at Dakar University Hospital: benefit of manual intrauterine aspiration. Med Trop. 2007;67:163-6.

Graziosi GCM, Mol BW, Ankum WM, Bruinse HW. Management of early pregnancy loss. Int J Gynecol Obstet. 2004;86:337-46.

Tong S, Kaur A, Walker SP, Bryant V, Onwude JL, Permezel M. Miscarriage risk for asymptomatic women after a normal first-trimester prenatal visit Obstet Gynecol. 2008;111:710-14.

Reeves MF, Lohr PA, Harwood BJ, Creinin MD. Ultrasonographic endometrial thickness after medical and surgical management of early pregnancy failure Obstet Gynecol. 2008;111:106-12.

Delabaere F. Epidemiology of pregnancy loss. J Gynecol Obstét Biol Reprod. 2014;43:764-75.

Lejeune V. Repeated spontaneous miscarriages: etiological assessment and management of subsequent pregnancies. J Gynecol Obstet Biol Rep. 2010;39:11-6.

Rai R, Regan L. Recurrent miscarriage. Lancet. 2006;368:601-11.

Ancel PY, Cubizolles MJ, Renzo GC, Papiernik E, Breart G. Risk factors for 14-21 week abortions: a case-control study in Europe. Hum Reprod. 2000;15:2426-32.

Luise C, Jermy K, May C, Costello G, Collins W.P, Bourne TH. Outcome of expectant management of spontaneous first trimester miscarriage: observational study. BMJ. 2002;324:873-5.

Maru L, Verma M, Khan T. Reinforcing the vast difference between the outcomes of spontaneous versus induced miscarriages. Int J Reprod Contracept Obstet Gynecol. 2016;5:4031-6.

Blohm F, Friden B, Christensen JJ. Expectant management of first trimester miscarriage in clinical practice. Acta Obstet Gynecol Scand. 2003;82:654-8.

Ksouri H, Zitouni M, Achour W, Makni S, Ben Hassen A. Fetal loss and repeated spontaneous abortions of immunological origin. Ann Med Interne. 2003;154(4):233-47.

Stephenson MD, Awartani KA, Robinson WP. Cytogenetic analysis of miscarriages from couples with recurrent miscarriage: a case-control study. Hum Reprod. 2002;17:446-51.

Palem G, Pal SJ. Maternal and fetal outcome of malaria in pregnancy. Int J Reprod Contracept Obstet Gynecol. 2019;8:4040-4.






Original Research Articles