How much antibiotic for cesarean section and hysterectomy: short course versus long course

Authors

  • Amol M. Valvi Department of Obstetrics and Gynecology, MIMSR Medical College, Latur, Maharashtra, India
  • Arun R. Mahale Department of Obstetrics and Gynecology, MIMSR Medical College, Latur, Maharashtra, India
  • Pankaj N. Baravkar Department of Obstetrics and Gynecology, MIMSR Medical College, Latur, Maharashtra, India

Keywords:

Cesarean section, Hysterectomy, Short course antibiotic, Long course antibiotic, Wound infection, Febrile morbidity

Abstract

Background: Objective of current study was to compare cost and efficacy of short course and long course prophylactic antibiotics for hysterectomy and cesarean section.

Methods: The current study is observational study. It has two antibiotic regimens a short course and a long course and these are compared for average duration of antibiotics, average cost of antibiotics, and outcome measures such as wound infection and febrile illness. Data were analyzed using t test, Chi-squared test, Epi info software used for analysis.

Results: The short course low cost regimen is as effective as more expensive long course regimen, with no significant difference of wound infections and febrile morbidity (P >0.05).

Conclusions: No statistical difference as regard wound infection and febrile morbidity in short course and long course of prophylactic antibiotic therapy in cesarean section and hysterectomy. There is statistical difference in antibiotic cost between two regimen, short course and long course for cesarean section and hysterectomy. The cost of antibiotic is 5.53 times less in short course regimen for cesarean section and hysterectomy when compared with long course regimen.

References

ACOG. Practice bulletin on antibiotic prophylaxis. J Obstet Gynaecol. 2009;113:1180-9.

Berek S. Berek & Novak's Gynecology. 14th Edition. Lippincott Williams & Wilkins; 2007.

Schorge JO, Schaffer JI, Halvorson LM, Hoffman BL, Bradshaw KD, Cunningham FG. In: Schorge JO, Schaffer JI, editors. Williams Gynecology. New York, NY: McGraw Hill; 2008.

Chelmow D, Ruheli MS, Haung E. Prophylactic use of antibiotics for non labouring women undergoing for LSCS. Am J Obstet Gynaecol. 2001;184:656-61.

Parulekar P, Kumar S, Awasthi RT, et al. A single dose of cefotaxime: as a prophylaxis during cesarean section. J Obstet Gynaecol India. 2001;51:118-21.

Joseph T. Dipiro, Richard P. Cheung, Talmadge A. Bowden, John A. Mansberger. Single dose systemic antibiotic prophylaxis of surgical wound infection. Am J Surg. 1986;152:552-9.

Indian Drug Review (IDR). Drug triple i compendium. UBM Medicaindia Private Limited, Bangalore. 2013;XIX(5):268.

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Published

2017-01-02

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Original Research Articles