Combined factor VIII and IX deficiency: role in puberty menorrhagia: a case report

Authors

  • Bhawana Tiwary Department of Obstetrics & Gynaecology, AIIMS, Phulwari Sharif, Patna, Bihar, India
  • Hemali Heidi Sinha Department of Obstetrics & Gynaecology, AIIMS, Phulwari Sharif, Patna, Bihar, India
  • Vivek Kumar Pandey Department of Pathology, Darbhanga Medical College, Darbhanga, Bihar, India

DOI:

https://doi.org/10.18203/2320-1770.ijrcog20160895

Keywords:

Menorrhagia, Hereditary bleeding disorders, Puberty menorrhagia, Factor VIII and IX deficiency

Abstract

The prevalence of menorrhagia in adolescent populations with bleeding disorders varies between 14% to 48%. Hereditary bleeding disorders are an important cause of puberty menorrhagia and the consequences can be life threatening. We report a case of 12 years old girl, known case of Factor VIII and IX deficiency who presented to our centre with menorrhagia at menarche. This case is reported as combined factor deficiency is a rarity. Early diagnosis, consultation with haematologist and appropriate treatment are essential.

References

Bevan JA. Bleeding disorders: A common cause of menorrhagia in adolescents. J Pediatr. 2001;138(6):856-61

Mikhail S, Varadarajan R, Kouides P. The prevalence of hemostasis in adolescents with menorrhagia referred to a haemophilia treatment centre. Hemophilia. 2007;13:627-32.

Kenneth Kaushansky. Inherited deficiencies of coagulation factor II, V, VIII, X, XI, XIII, combined deficiency of factor V and VIII and of vitamin K dependent factors. Kenneth Kaushansky, Ernest Beutler, Marshall A Lichtman. Williams hematology. 8th edition. China, 2010. The McGraw-Hill companies, Inc.

Fogarty PF, Kessler CM. Hemophilia A and B. In Kitchens C, Kessler C, Konkle B, editors. Consultative hemostasis and Thrombosis; 3rd ed.Elsevier. 2013:50-53.

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Published

2016-12-27

Issue

Section

Case Reports