Combined factor VIII and IX deficiency: role in puberty menorrhagia: a case report


  • Bhawana Tiwary Department of Obstetrics & Gynaecology, AIIMS, Phulwari Sharif, Patna, Bihar, India
  • Hemali Heidi Sinha Department of Obstetrics & Gynaecology, AIIMS, Phulwari Sharif, Patna, Bihar, India
  • Vivek Kumar Pandey Department of Pathology, Darbhanga Medical College, Darbhanga, Bihar, India



Menorrhagia, Hereditary bleeding disorders, Puberty menorrhagia, Factor VIII and IX deficiency


The prevalence of menorrhagia in adolescent populations with bleeding disorders varies between 14% to 48%. Hereditary bleeding disorders are an important cause of puberty menorrhagia and the consequences can be life threatening. We report a case of 12 years old girl, known case of Factor VIII and IX deficiency who presented to our centre with menorrhagia at menarche. This case is reported as combined factor deficiency is a rarity. Early diagnosis, consultation with haematologist and appropriate treatment are essential.


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