Uterine leiomyoma presenting with unusual pathological features: a series of two cases
Keywords:Leiomyoma, Cervical, Uterine, Chondroid metaplasia
Leiomyomas are benign and most common smooth muscle neoplasms that can occur in any organ, most commonly in uterus, small bowel and esophagus. Leiomyomas may have unusual presentations either in form of location or various secondary changes like hyaline, myxoid, red degeneration, chondroid metaplasia, sarcomatous change, etc. We present two unusual cases of leiomyomas, one involving an unusual location (giant cervical fibroid) and the other a uterine leiomyoma with rare pure chondroid metaplasia. Both these entities are rare and hold importance in the differential diagnosis because it is imperative to differentiate the giant cervical fibroid from any ovarian neoplasm or procidentia and chondroid metaplasia from any other mesenchymal/mixed uterine tumor. Moreover giant leiomyomas require expert hands during surgical removal.
Parker WH. Etiology, symptomatology, and diagnosis of uterine myomas. Fertil Steril. 2007;87(4):725-36.
Bell SW, Kempson RL, Hendrickson MR. Problematic uterine smooth muscle neoplasms. A clinicopathologic study of 213 cases. Am J Surg Pathol. 1994;18(6):535-58.
Kumar P, Malhotra N. Tumours of the corpus uteri. In: Jeffcoat’s Principles of Gynaecology. New Delhi: Jaypee Brothers Medical Publisher (Pvt.) Ltd. 2008:487-516.
Kawakami S, Togashi K, Konishi I, Kimura I, Fukuoka M, Mori T. Red degeneration of uterine leiomyoma: MR appearance. J Comput Assist Tomogr. 1994;18(6):925-8.
Zaloudek CJ, Hendrickson MR. Mesenchymal tumors of the uterus. In: Blaustein’s Pathology of the Female Genital Tract. New York: Springer Verlag. 2002:561-615.
Oliva E. Pure Mesenchymal and Mixed Müllerian Tumors of the Uterus. In: Gynecologic Pathology. China: Elsevier Churchill Livingstone. 2009:261-330.
Evans AT III, Pratt JH. A giant fibroid uterus. Obstet Gynecol. 1979;54:385-6.
Basnet N, Banerjee B, Badani U, Tiwari A, Raina A, Pokharel H, et al. An unusual presentation of huge cervical fibroid. Kathmandu Univ Med J. 2005;3(2):173-4.
Suneja A, Taneja A, Guleria K, Yadav P, Agarwal N. Incarcerated procidentia due to cervical fibroid: an unusual presentation. Aust N Z J Obstet Gynaecol. 2003;43(3):252-3.
Lugo M, Putong PB. Metaplasia. An overview. Arch Pathol Lab Med. 1984;108(3):185-9.