Polycystic ovarian syndrome: pathogenesis and management


  • Coumba Aicha Thiam Department of Obstetrics and Gynaecology, Zhongnan Hospital of Wuhan University, Wuhan, Hubei, China
  • Malyn M. L. K. Antoine Department of Endocrinology, Zhongnan Hospital of Wuhan University, Wuhan, Hubei, China
  • Chrystal D. Antoine-Frank Department of Anatomical Sciences, St. George’s University, True Blue, Grand Anse, St. George, Grenada, West Indies




Hyperandrogenemia, Insulin resistance, Polycystic ovarian syndrome, Type-2 diabetes mellitus


Polycystic ovarian syndrome (PCOS) is an endocrine disorder that commonly affects women of reproductive age. Its prevalence varies quite significantly and its clinical presentation includes: reproductive, metabolic and psychological issues.  PCOS develops due to a variety of factors some of which are not yet fully understood. Due to the complexity in the development and presentation of this condition, the management of PCOS in most instances is complicated and involves the combination of pharmacological, non-pharmacological and surgical interventions. This review discusses the pathogenesis and management of PCOS as means of providing information that would enhance understanding and control of this disease.

Author Biographies

Coumba Aicha Thiam, Department of Obstetrics and Gynaecology, Zhongnan Hospital of Wuhan University, Wuhan, Hubei, China


Malyn M. L. K. Antoine, Department of Endocrinology, Zhongnan Hospital of Wuhan University, Wuhan, Hubei, China


Chrystal D. Antoine-Frank, Department of Anatomical Sciences, St. George’s University, True Blue, Grand Anse, St. George, Grenada, West Indies

clinical instructor content manager, histology and cell biology


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