DOI: http://dx.doi.org/10.18203/2320-1770.ijrcog20210734

Correlation between male and female genital tuberculosis: a prospective analytical study

Aarushi Chaudhary, Prabhjot Kaur, Richa Kansal, Vikas Dhillon, Isha Bansal

Abstract


Background: Genital tuberculosis is an unusual extrapulmonary manifestation of tuberculosis, often seen in middle-aged men with renal or pulmonary disease. The most common male genital sites of tuberculous infection are the epididymis and prostate. It is also an important cause of female infertility in the world, especially in developing countries. Majority of infertility cases are due to involvement of the fallopian tubes. Hardly any study has been done to establish correlation between male and female genital TB. We have evaluated the same in severe oligospermic/ azoospermic males and established a definite correlation. Objective was to establish a definite correlation between female and male genital tuberculosis in patients with male factor infertility.

Methods: 100 severe oligozoospermic/azoospermic males presenting with infertility between April 2011 and January 2016 were enrolled and worked up for genital tuberculosis. Their female partners were worked up for female genital TB and correlation established.

Results: Out of 100 patients with severe oligospermia or azoospermia who tested positive for TB quantiferon gold test. 18% female partners tested positive for TB quantiferon gold test.

Conclusions: Tubercular work up of both partners is desired in couples with male factor infertility especially in long standing infertility to achieve optimum pregnancy outcome with ART.


Keywords


ART, Infertility, Tuberculosis

Full Text:

PDF

References


World Health Organization (‎2018)‎. Global tuberculosis report 2018. World Health Organization. Available from: https://apps.who.int/iris/handle/ 10665/274453. Accessed on 3 December 2019.

Central TB Division, Directorate General of Health Services. India TB. Report: Revised National Tuberculosis Control Programme: Annual status report. New Delhi. Ministry of Health and Family Welfare; 2018.

Golden MP, Vikram HR. Extrapulmonary tuberculosis: An overview. Am Fam Phys. 2005;72:1761-8.

Kumar S, Sharma JB. Female genital tuberculosis. In: Sharma SK, Mohan A, eds. Tuberculosis, 3rd edn. Delhi: Jaypee; 2015:362-371.

Neonakis IK, Spandidos DA, Petinaki E. Female genital tuberculosis: A review. Scand J Infect Dis. 2011;43:564-72.

Sharma JB. Tuberculosis and obstetric and gynecological practice. In: Studd J, Tan SL, Chervenak FA, eds. Progress in obstetrics and gynaecology, Vol. 18. Philadelphia: Elsevier; 2008:395-427.

Sharma JB. Current diagnosis and management of female genital tuberculosis. J Obstet Gynaecol India. 2015;65:362-71.

Gorse GJ, Belshe RB. Male genital tuberculosis: a review of the literature with instructive case reports. Rev Infect Dis. 1985;7(4):511-24.

Jacob JT, Nguyen TM, Ray SM. Male genital TB. Lancet Infect Dis. 2008;8(5):335-42.

Shah HU, Sannananja B, Baheti AD, Udare AS, Badhe PV. Hysterosalpingography and ultrasonography findings of female genital tuberculosis. Diagnost Intervent Radiol. 2015;21(1):10.

Abbara A, Davidson RN. Etiology and management of genitourinary tuberculosis. Nat Rev Urol. 2011;8:678-88.

Figueiredo AA, Lucon AM. Urogenital tuberculosis: update and review of 8961 cases from world literature. Rev Urol. 2008;10:207-17.

Kulchavenya E, Khomyakov V. Male genital tuberculosis in Siberians. World J Urol. 2006;24:74-8.

Gupta NP, Kumar R, Mundada OP, Aron M, Hemal AK, Dogra PN, et al. Reconstructive surgery for the management of genitourinary tuberculosis: a single center experience. J Urol. 2006;175:2150-4.

Gorse GJ, Belshe RB. Male genital tuberculosis: a review of the literature with instructive case reports. Rev Infect Dis. 1985;7:511-24.

Hemal AK, Aron M. Orthotopic neobladder in management of tubercular thimble bladders: initial experience and long-term results. Urology. 1999;53:298-301.

Jacob JT, Nguyen TM, Ray SM. Male genital tuberculosis. Lancet Infect Dis. 2008;8:335-42.

Christensen WI. Genitourinary tuberculosis. Review of 102 cases. Medicine. 1974;53:377-90.

Aphonin A, Perezmanas E, Toporkova E, Khodakovsky E. Tuberculous infection as sexually transmitted infection. Vestnik Poslediplomnogo Obrazovaniya. 2006;3-4:69-71.

Kulchavenya E. Male Genital Tuberculosis. In: Urogenital Tuberculosis: Epidemiology, Diagnosis, Therapy. Springer, Cham; 2014:83-93.

Baxi A, Neema H, Kadi P, Baxi D, Kaushal M. Prevalence of male genital tuberculosis in indian infertile couples and its correlation with female genital tuberculosis. J South Asian Feder Obst Gynaecol. 2016;8(1):13-5.