Leiomyosarcoma: a rare complication of uterine fibroid

Authors

  • Shazia Parveen Department of Obstetrics and Gynaecology, JN Medical College and Hospital, AMU, Aligarh, UP, India
  • Noor Afshan Sabzposh Department of Obstetrics and Gynaecology, JN Medical College and Hospital, AMU, Aligarh, UP, India
  • Amina Kuraishy Department of Obstetrics and Gynaecology, JN Medical College and Hospital, AMU, Aligarh, UP, India

Keywords:

Fibroid, Leiomyosarcoma, Mesodermal tumour

Abstract

Uterine sarcomas are rare tumours of mesodermal origin. Malignant change occurring in uterine fibroid is termed as leiomyosarcoma. They constitute around 2-6 % uterine malignancies and 25-36% of uterine sarcomas. The tumour is common in women between the age group 40-50 years. It has an aggressive course & usually metastasis goes to the lungs. The prognosis for women with uterine sarcoma primarily depends on the extent of disease at the time of diagnosis and mitotic index. Women with tumor size >5 cm in maximum diameter have poor prognosis. These tumours should be diagnosed and managed with no delay and must be followed vigilantly as the rate of recurrence & metastasis is very high.

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References

Jitendra K. Patel, Kelley L Cervellione, Muhammad Sulh, Avani A. Patel, Jonas Gintautas. A rare case of uterine leiomyosarcoma metastasis to the duodenum. Proc West Phamacol Soc. 2009;52:8-10.

Giuntoli, RL 2nd, Metzinger DS, Di Marco CS, Keeney GL. Retrospective review of 208 patients with leiomyosarcoma of the uterus: prognostic indicators, surgical management, and adjuvant therapy. Gynaecol Oncol. 2003;89:460-9.

Major FJ, Blessing JA, Silverberg SG, Morrow CP, Creasman WT, Currie JL, Yordan F, Brady MF. Prognostic factors in early stage uterine sarcoma: a gynaecologic oncology group study. Cancer. 1993;71(40):1702-9.

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Published

2017-01-02

How to Cite

Parveen, S., Sabzposh, N. A., & Kuraishy, A. (2017). Leiomyosarcoma: a rare complication of uterine fibroid. International Journal of Reproduction, Contraception, Obstetrics and Gynecology, 3(2), 486–487. Retrieved from https://www.ijrcog.org/index.php/ijrcog/article/view/975

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Section

Case Reports