Serous tubal intraepithelial carcinoma: an incidental finding in laparotomy for tubo-ovarian mass in woman aged 35 years

Authors

  • Rinku Kumari Department of Obstetrics and Gynecology, Government Medical College, Kota, Rajasthan, India
  • Mamta Sharma Department of Obstetrics and Gynecology, Government Medical College, Kota, Rajasthan, India

DOI:

https://doi.org/10.18203/2320-1770.ijrcog20211161

Keywords:

STIC, Surgical staging, Case report

Abstract

Serous tubal intraepithelial carcinoma (STIC) is a precursor lesion for high-grade pelvic serous carcinoma. The incidence of STIC is estimated to occur in 0.6% to 6% of women who are BRCA positive or have a strong family history of breast or ovarian cancer. We report a rare case of serous tubal Intraepithelial carcinoma in young woman undergoing laparotomy for tubo-ovarian mass who diagnosed STIC on histopathological examination of specimen. Women diagnosed incidentally at surgery for benign condition should be considered for repeat surgical staging. Etiology and management are similar to epithelial ovarian cancer but stage at diagnosis, lymphatic spread and overall survival appear to be different.

 

Author Biography

Rinku Kumari, Department of Obstetrics and Gynecology, Government Medical College, Kota, Rajasthan, India

Department of Obstetrics and Gynecology

All India rank-6700

References

Benedet JL, Bender H, Jones H 3rd, Ngan HY, Pecorelli S. FIGO staging classifications and clinical practice guidelines in the management of gynecological cancers. FIGO Committee on Gynecologic Oncology. Int J Gynaecol Obstet. 2000;70:209-62.

Woolas R, Jacobs I, Davies AP, Leake J, Brown C, Grudzinskas JG, et al. What is the true incidence of primary fallopian tube carcinoma. Int J Gynecol Cancer. 1994;4:384-8.

FIGO Report. Carcinoma of the fallopian tube: patients treated in 1990–1992 - distribution by age groups. J Epidemiol Biostat. 1998;3:93.

Yuen JH, Wong CG, Lam CH. Preoperative sonographic diagnosis of primary fallopian tube carcinoma. J Ultrasound Med. 2002;21:1171-3.

Inal MM, Hanhan M, Pilanci B, TinarS. Fallopian tube malignancies: experience of Social Security Agency Agean Maternity Hospital. Int J Gynecol Cancer. 2004;14:595-9.

Eddy GL, Copeland LJ, Gershenson DM, Atkinson EN, Wharton JT, Rutledge FN. Fallopian tube carcinoma. Obstet Gynecol. 1984;64:546-52.

Finch A, Shaw P, Rosen B, Murphy J, Narod SA, Colgan TJ. Clinical and pathologic findings of prophylactic salpingo-oophorectomies in 159 BRCA1 and BRCA2 carriers. Gynecologic Oncology. 2006;100(1):58-64.

Wethington SL, Park KJ, Soslow RA. Clinical outcome of isolated Serous tubal intraepithelial carcinomas (STIC). International Journal of Gynecological Cancer. 2013;23(9):1603-11.

Manchanda R, Abdelraheim A, Johnson M. Outcome of risk-reducing salpingo-oophorectomy in BRCA carriers and women of unknown mutation status,” BJOG: An International Journal of Obstetrics and Gynaecology. 2011;118(7):814-24.

Romagosa C, Torne A, Iglesias X, Cardesa A, Ordi J. Carcinoma of the fallopian tube presenting as acute pelvic inflammatory disease. Gynecol Oncol. 2003;89:181-4.

Goswami PK, Kerr-Wilson R, McCarthy K. Cancer of the fallopian tube. The Obstetrician & Gynaecologist. 2006;8:147-52.

Downloads

Published

2021-03-24

Issue

Section

Case Reports