A rare association of uterine leiomyoma with mesenteric vein thrombosis and bowel gangrene: case report


  • Rajneesh Rawat Department of General Surgery, IGGMC, Nagpur, Maharashtra, India http://orcid.org/0000-0002-9049-8230
  • Manik Gedam Department of General Surgery, IGGMC, Nagpur, Maharashtra, India
  • Jyoti Baghel Department of Obstetrics and Gynecology, AIIMS Nagpur, Maharashtra, India
  • Shalini Baghel Department of Obstetrics and Gynaecology, SN Medical College, Agra, Uttar Pradesh, India




Uterine leiomyoma, Acute abdomen, Portal vein thrombosis, Superior mesenteric vein thrombosis, Bowel gangrene, Case report


Uterine fibroids are the most common benign pelvic tumors in women. There are many complications reported with fibroids. However, mesenteric vein thrombosis and small bowel gangrene caused by a uterine fibroid are rare. This manuscript reports a rare case of 40 year female with a large uterine fibroid associated with mesenteric vein thrombosis and bowel ischemia. She underwent exploratory laparotomy in which resection of gangrenous bowel including jejunum and ileum was done along with left sided jejunostomy and right sided ileostomy. Total abdominal hysterectomy with bilateral salpingooophorectomy was done followed by jejunoileal anastomosis 6 weeks later. Hence, in patients presenting with acute abdomen and uterine fibroids, bowel gangrene must be included in the differential diagnosis.

Author Biography

Jyoti Baghel, Department of Obstetrics and Gynecology, AIIMS Nagpur, Maharashtra, India

Dr. Jyoti Baghel, Senior Resident

Department of Obstetrics and Gynecology, AIIMS Nagpur

Email id :bagheljyoti@aiimsnagpur.edu.in

Phone no: 9585895803


Baird DD, Dunson DB, Hill MC, Cousins D, Schectman JM. High cumulative incidence of uterine leiomyoma in black and white women: ultrasound evidence. Am J Obstet Gynecol.2003;188(1):100-7.

Evans P, Brunsell S. Uterine fibroid tumors: diagnosis and treatment. Am Fam Physician. 2007;75:1503-8.

Sujindra E, Sabita SC, Bupathy A. Uterine myomatosis and portal vein thrombosis: a rare association. Int J Reprod Contracept Obstet Gynecol. 2016;5:3265-7.

Hawes J, Lohr J, Blum B, Bhati A, Bhaskaran J, Engel A. Large uterine fibroids causing mechanical obstruction of the inferior vena cava and subsequent thrombosis: a case report. Vasc Endovascular Surg. 2006;40:425-7.

Bonito M, Gulem L, Basili R, Brunetti G, Roselli D. Thrombosis associated with a large uterine myoma: case report. Clin Exp Obstet Gynecol. 2007;34:188-9.

Falcone M, Serra P. Massive pulmonary embolism in a woman with leiomyomatous uterus causing pelvic deep venous thrombosis. Annali Italiani di Medicina Interna. 2005;20:104-7.

Hamid H. Sheikh. A rare case of mesenteric vein thrombosis and small intestinal gangrene caused by a pedunculated fundal uterine fibroid is presented. The causative mechanism and management are discussed. Am J Obstet GynecoI. 1998;179:830-1.

Beguin Y. Erythropoietin and platelet production. Haematologica. 1999;84:541-7.

Karpatkin S, Garg SK, Freedman ML. Role of iron as a regulator of thrombopoiesis. Am J Med. 1974;57:521-5.

Balci K, Utku U, Asil T, Büyükkoyuncu N. Deep cerebral vein thrombosis associated with iron deficiency anemia in adults. J Clin Neurosci. 2007;14:181-4.

Bodner-Adler B, Nather A, Bodner K, et al. Expression of thrombospondin 1 (TSP 1) in patients with uterine smooth muscle tumors: an immunohistochemical study. Gynecol Oncol. 2006;103:186-9.

Wolańska M, Bańkowski E. Fibroblast growth factors (FGF) in human myometrium and uterine leiomyomas in various stages of tumour growth. Biochimie. 2006;88:141-6.






Case Reports