Per-operative anesthetic complications during lower segment caesarean section and their management

Authors

  • Sabrin Farhad Department of Obstetrics and Gynecology, Uttara Adhunik Medical Hospital, Dhaka, Bangladesh
  • Tahmina Akter Department of Obstetrics and Gynecology, Uttara Adhunik Medical Hospital, Dhaka, Bangladesh
  • M. Ridwanul Ferdous Department of Cardiology, Continental Hospital PLC, Dhaka, Bangladesh

DOI:

https://doi.org/10.18203/2320-1770.ijrcog20263409

Keywords:

Cesarean section, General anesthesia, Hypotension, Peroperative complications, Spinal anesthesia

Abstract

Background: Lower uterine segment caesarean section (LUCS) is one of the most frequently performed surgical procedures worldwide. Both spinal anesthesia (SA) and general anesthesia (GA) are commonly employed, each carrying a distinct profile of per-operative complications. Prompt recognition and management of these complications, including rare but serious events, are critical for maternal safety. Objective was to determine the frequency, types, and management outcomes of per-operative anesthetic complications during LUCS under spinal and general anesthesia.

Methods: A prospective cohort study was conducted at the department of gynecology and obstetrics, Uttara Adhunik Medicak College Hospital, Dhaka, Bangladesh, from January 2025 to December 2025. A total of 163 pregnant women undergoing LUCS were enrolled using purposive sampling. Data on intraoperative complications under SA (n=112) and GA (n=51) were recorded. Management strategies and immediate outcomes were analyzed using SPSS version 23.0.

Results: Complications occurred in 48 patients (29.4%). Under SA, hypotension (32.1%), bradycardia (12.5%), and rare complications, including high spinal (1.8%) and transient radicular irritation (0.9%), were observed. Under GA, desaturation (7.8%), failed intubation (3.9%), and one case of anaphylaxis to rocuronium (2.0%) occurred. All complications were managed successfully without maternal mortality.

Conclusions: Per-operative anesthetic complications during LUCS are not uncommon. While hypotension under spinal anesthesia predominates, rare complications such as high spinal and anaphylaxis require high vigilance. Protocol-driven management ensures favorable outcomes.

References

Betran AP, Ye J, Moller AB, Souza JP, Zhang J. Trends and projections of caesarean section rates: global and regional estimates. BMJ Glob Health. 2021;6(6):e005671.

Boerma T, Ronsmans C, Melesse DY, Barros AJ, Barros FC, Juan L, et al. Global epidemiology of use of and disparities in caesarean sections. Lancet. 2018;392(10155):1341-8.

Sandall J, Tribe RM, Avery L, Mola G, Visser GH, Homer CS, et al. Short-term and long-term effects of cesarean section on the health of women and children. Lancet. 2018;392(10155):1349-57.

Umar BU, Haque M. Growing concern over rising caesarean section rates: is it a problem for low-and middle-income countries only? Adv Hum Biol. 2022;12(2):93-100.

Devroe S, Van de Velde M, Rex S. General anesthesia for cesarean section. Curr Opin Anesthesiol. 2015;28(3):240-6.

Roofthooft E, Joshi GP, Rawal N, Van de Velde M. PROSPECT guideline for elective cesarean section: a reply. Anaesthesia. 2021;76(9):1280.

Kinsella SM, Carvalho B, Dyer RA, Fernando R, McDonnell N, Mercier FJ, et al. International consensus statement on the management of hypotension with vasopressors during caesarean section under spinal anaesthesia. Anaesthesia. 2018;73(1):71.

Odor PM, Bampoe S, Lucas DN, Moonesinghe SR, Andrade J, Pandit JJ, et al. Incidence of accidental awareness during general anaesthesia in obstetrics: a multicentre, prospective cohort study. Anaesthesia. 2021;76(6):759-76.

Mushambi MC, Kinsella SM, Popat M, Swales H, Ramaswamy KK, Winton AL, et al. Obstetric Anaesthetists’ Association and Difficult Airway Society guidelines for the management of difficult and failed tracheal intubation in obstetrics. Anaesthesia. 2015;70(11):1286-306.

Quinn A, Kinsella S, Gorton H, Knight M, Columb M, Robson S, et al. Neonatal outcomes after failed tracheal intubation during obstetric general anaesthesia for caesarean section: Secondary analysis of a UKOSS case-control study. Eur J Obstet Gynecol Reprod Biol. 2017;217.

Russell R, Laxton C, Lucas DN, Niewiarowski J, Scrutton M, Stocks G. Treatment of obstetric post-dural puncture headache. Part 1: conservative and pharmacological management. Int J Obstet Anesth. 2019;38:93-103.

Harper NJ, Cook TM, Garcez T, Farmer L, Floss K, Marinho S, et al. Anaesthesia, surgery, and life-threatening allergic reactions: epidemiology and clinical features of perioperative anaphylaxis in the 6th National Audit Project (NAP6). Br J Anaesth. 2018;121(1):159-71.

Mushambi MC, Fakiris K, Kunte R. General anesthesia in the parturient. Int Anesthesiol Clin. 2021;59(3):78-89.

Khan MY, Saeed M, Yasin B, Ameer K, Noor N. Impact of General anesthesia versus combined epidural and general anesthesia on postoperative complications and mortality in elective abdominal aortic aneurysm surgeries. Pak Armed Forces Med J. 2023;73(2):405.

Shrestha R, Upadhyay SK, Khatri B, Bhattarai JR, Kayastha M, Upadhyay MP. BMI, waist to height ratio and waist circumference as a screening tool for hypertension in hospital outpatients: a cross-sectional, non-inferiority study. BMJ Open. 2021;11(11):e050096.

Dyer RA, Reed AR, van Dyk D, Arcache MJ, Hodges O, Lombard CJ, et al. Hemodynamic effects of ephedrine, phenylephrine, and the coadministration of phenylephrine with oxytocin during spinal anesthesia for elective cesarean delivery. Anesthesiology. 2009;111(4):753-65.

Guglielminotti J, Landau R, Ing C, Li G. Temporal trends in the incidence of post-dural puncture headache following labor neuraxial analgesia in the United States, 2006 to 2015. Int J Obstet Anesth. 2021;45:90-8.

Taylor CR, Dominguez JE, Habib AS. Obesity and obstetric anesthesia: current insights. Local Reg Anesth. 2019:111-24.

Yoon S, Gianturco SL, Pavlech LL, Storm KD, Yuen MV, Mattingly AN. Epinephrine bitartrate: Summary Report. 2021.

Sobhy S, Zamora J, Dharmarajah K, Arroyo-Manzano D, Wilson M, Navaratnarajah R, et al. Anaesthesia-related maternal mortality in low-income and middle-income countries: a systematic review and meta-analysis. Lancet Glob Health. 2016;4(5):e320-7.

Garcia D, Kehar M, Khan ES, Mendonca R, Girshin M, Girshin M. Multiple episodes of severe bronchospasm during general anesthesia: a case report. Cureus. 2022;14(1).

Kalangara J, Vanijcharoenkarn K, Lynde GC, McIntosh N, Kuruvilla M. Approach to perioperative anaphylaxis in 2020: updates in diagnosis and management. Curr Allerg Asthma Rep. 2021;21(1):4.

Laguna JJ, Archilla J, Doña I, Corominas M, Gastaminza G, Mayorga C, et al. Practical guidelines for perioperative hypersensitivity reactions. J Investig Allergol Clin Immunol. 2018;28(4):216-32.

Tan JQ, Wu HL, Wang YC, Cata JP, Chen JT, Cherng YG, et al. Antiemetic prophylaxis with droperidol in morphine-based intravenous patient-controlled analgesia: a propensity score matched cohort study. BMC Anesthesiol. 2023;23(1):351.

Bishop D, Dyer RA, Maswime S, Rodseth RN, Van Dyk D, Kluyts HL, et al. Maternal and neonatal outcomes after caesarean delivery in the African Surgical Outcomes Study: a 7-day prospective observational cohort study. Lancet Glob Health. 2019;7(4):e513-22.

Downloads

Published

2026-09-28

How to Cite

Farhad, S., Akter, T., & Ferdous, M. R. (2026). Per-operative anesthetic complications during lower segment caesarean section and their management. International Journal of Reproduction, Contraception, Obstetrics and Gynecology, 15(10), 3805–3810. https://doi.org/10.18203/2320-1770.ijrcog20263409

Issue

Section

Original Research Articles