Sociodemographic and menstrual profile of infertile women with endometriosis: a comparative cross-sectional analysis from a tertiary centre in Rajasthan

Authors

  • Shivangi Yadav Department of Obstetrics and Gynecology, S. M. S. Medical College, Jaipur, Rajasthan, India
  • Nupur Lauria Department of Obstetrics and Gynecology, S. M. S. Medical College, Jaipur, Rajasthan, India
  • Anchal Department of Obstetrics and Gynecology, S. M. S. Medical College, Jaipur, Rajasthan, India
  • Manisha Kumari Department of Obstetrics and Gynecology, S. M. S. Medical College, Jaipur, Rajasthan, India

DOI:

https://doi.org/10.18203/2320-1770.ijrcog20263436

Keywords:

BMI, Endometriosis, Infertility, Laparoscopy menstrual cycle, Sociodemographic, Socioeconomic status

Abstract

Background: Endometriosis disproportionately affects women during their reproductive years and has been associated with various sociodemographic and menstrual factors. Understanding these associations is critical for early identification and improved public health strategies, particularly in resource-constrained settings. Data on the sociodemographic profile of endometriosis from North India remain sparse.

Methods: A hospital-based cross-sectional comparative observational study of 60 infertile women (30 with laparoscopically confirmed endometriosis and 30 controls) was conducted at a tertiary care centre in Jaipur, between July 2023 and July 2025. Demographic, anthropometric, and menstrual data were collected. Chi-square, Fisher exact test, and unpaired t-test were used for analysis.

Results: No significant age difference was found between cases (mean 28.01±4.78 yrs) and controls (28.73±5.13 yrs; p=0.604). Women with endometriosis were significantly more likely to belong to higher socioeconomic status (53.33% upper class vs. 26.66% in controls; p=0.043) and had significantly lower BMI (21.26±2.91 vs. 23.26±3.26 kg/m²; p=0.0147). Shorter menstrual cycle length was significantly associated with endometriosis (mean 26.97±3.91 vs. 30.13±4.66 days; p=0.0013). No significant differences in religion, literacy, or parity were observed.

Conclusions: Higher socioeconomic status, lower BMI, and shorter menstrual cycle length are significantly associated with endometriosis in infertile women. These factors may serve as clinical flags to prompt earlier investigation in appropriate patient populations.

References

Tsamantioti ES, Mahdy H. Endometriosis. In: StatPearls. Treasure Island (FL): StatPearls Publishing; 2024.

Udupa KS, Phukan P, Saikia N, Dutta A. Study on epidemiology of endometriosis in North East India. Int J Reprod Contracept Obstet Gynecol. 2023;12:1770-4.

Ramani Devi T, Kadalmani B, Anchana Devi C. Epidemiology of Endometriosis in Tamil Nadu, India. APJHS. 2022;9(3):15-24.

Chandra R, Soumya, Jakhar A. Association between endometriosis and hyperprolactinemia in infertile women. Int J Current Research. 2020;12(12):15218-21.

Hediger ML, Hartnett HJ, Louis GMB. Association of endometriosis with body size and figure. Fertil Steril. 2005;84(5):1366-74.

Wei M, Cheng Y, Bu H, Zhao Y, Zhao W. Length of menstrual cycle and risk of endometriosis: a meta-analysis of 11 case-control studies. Medicine (Baltimore). 2016;95(9):e2922.

Eisenberg VH, Weil C, Chodick G, Shalev V. Epidemiology of endometriosis: a large population-based database study from a healthcare provider with 2 million members. BJOG. 2018;125(1):55-62.

Jenabi E, Fereidooni B, Khazaei S. The association between parity and the risk of endometriosis: a meta-analysis. Erciyes Med J. 2021;43(3):228-32.

Cardoso JV, Machado DE, da Silva MC, Berardo PT, Ferrari R, Abrão MS, et al. Epidemiological profile of women with endometriosis: a retrospective descriptive study. Rev Bras Saude Mater Infant. 2020;20(4):1057-67.

Esmaeilzadeh S, Mirabi P, Basirat Z, Zeinalzadeh M, Khafri S. Association between endometriosis and hyperprolactinemia in infertile women. Iran J Reprod Med. 2015;13(3):155-60.

Parasar P, Ozcan P, Terry KL. Endometriosis: epidemiology, diagnosis and clinical management. Curr Obstet Gynecol Rep. 2017;6(1):34-41.

De Corte P, Klinghardt M, von Stockum S, Heinemann K. Time to diagnose endometriosis: current status, challenges and regional characteristics-a systematic literature review. BJOG. 2025;132(2):118-30.

Fryer J, Mason-Jones AJ, Woodward A. Understanding diagnostic delay for endometriosis: A scoping review. MedrXiv. 2024:2024-01.

Liu F, Yuan S, Yan Q, Yang S, Yan W, Xiang T, et al. Global trends in endometriosis burden, 1990-2021: a sociodemographic analysis using GBD 2021 data and projections to 2036. Int J Womens Health. 2026;18:560463.

Yu X, Shi L, Deng X, Zhang Y, Wang H. Global burden of endometriosis from 1990 to 2021 and projections to 2050: a comprehensive analysis based on the Global Burden of Disease Study 2021. Front Glob Womens Health. 2025;6:1613468.

Milla H, Ritonga MA, Bayuaji H, Heriyanto A, Direza FH. Association between body fat percentage and endometriosis severity based on American Association of Gynecologic Laparoscopists 2021 endometriosis classification. Int J Womens Health. 2026;18:582542.

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Published

2026-09-28

How to Cite

Yadav, S., Lauria, N., Anchal, & Kumari, M. (2026). Sociodemographic and menstrual profile of infertile women with endometriosis: a comparative cross-sectional analysis from a tertiary centre in Rajasthan. International Journal of Reproduction, Contraception, Obstetrics and Gynecology, 15(10), 3989–3993. https://doi.org/10.18203/2320-1770.ijrcog20263436

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Original Research Articles